Potential Use of Cell Free Fetal DNA at 13 Short Tandem Repeats Loci for Noninvasive Prenatal Paternity Test

Background : Prenatal paternity test is mostly performed by using Amniocentesis or Chorionic Villus Sampling (CVS) methods. However, these methods require invasive procedures, which are potentially harmful for both the mother and fetus. Currently, invention of Cell-Free Fetal DNA (cffDNA) has offered opportunity performing prenatal non-invasively. Materials Methods This study a cross sectional descriptive to detect cell free fetal at 13 STR loci amelogenin gene evaluate fetus gender, will be compared baby gender afterbirth. Healthy third semester pregnant women were included as participants. Inform consent biological father been provided. Result Four participants evaluated. In this study, in all participants, we found presence cffDNA almost loci. Some cannot detected due small amount All genders macthed four babies Conclusion The use potential non-invasive test. Additionally, ability method suggested.